
Sodium orthovanadate
CAS No. 13721-39-6
Sodium orthovanadate( —— )
Catalog No. M11533 CAS No. 13721-39-6
Sodium orthovanadate is a commonly used general inhibitor for PTP (protein tyrosine phosphatases), alkaline phosphatase (ALP) and ATPase.
Purity : >98% (HPLC)






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Biological Information
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Product NameSodium orthovanadate
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NoteResearch use only, not for human use.
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Brief DescriptionSodium orthovanadate is a commonly used general inhibitor for PTP (protein tyrosine phosphatases), alkaline phosphatase (ALP) and ATPase.
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DescriptionSodium orthovanadate is a commonly used general inhibitor for PTP (protein tyrosine phosphatases), alkaline phosphatase (ALP) and ATPase. Na3VO4 acts as a competitive inhibitor and is completely reversible upon the addition of EDTA or by dilution. The PTP activities are conveniently separable from the protein phosphoseryl and phosphothreonyl phosphatase (PSP) activities inhibited by Fluoride and EDTA. Vanadate is routinely used to preserve the protein tyrosyl phosphorylation state in cells, cell lysates, and protein tyrosine kinase assays. Sodium Orthovanadate is an inhibitor of AK and PFK.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetATPase
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Recptor(Na,K)-ATPase| Phosphatase
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number13721-39-6
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Formula Weight183.9
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Molecular FormulaNa3O4V
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Purity>98% (HPLC)
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SolubilityWater: 37 mg/mL (201.18 mM)
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SMILES[Na+].O=[V-3](=O)(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wu Y, et al. Acta Pharmacol Sin, 2005, 26(3), 345-352.
2. Cantley LC Jr, et al. J Biol Chem, 1977, 252(21), 7421-7423.
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